Affinity labelling of endothelin receptor and characterization of solubilized endothelin-endothelin-receptor complex
نویسندگان
چکیده
منابع مشابه
Upregulation of Endothelin-1/Endothelin A Receptor Expression Correlates with Heparanase Expression in Ovarian Carcinoma
Background: Heparanase and endothelin-1/endothelin A receptor (ET-1/ETAR) expressions increase in cancer. This condition enhances tumor progression and correlates with poor survival. Limited data are documented regarding the role of heparanase and ET-1/ETAR in epithelial ovarian cancer (EOC). We sought to characterize the correlation between heparanase and ET-1/ETAR in EOC.Methods: Thirty patie...
متن کاملDevelopmental changes in Endothelin-1 and Endothelin type A receptor expression in the lungs of chickens (Broiler versus layer)
Background: Broilers lung mechanisms that regulate endothelin (ET) in the lung are complex and poorly understood. Objectives: Methods: In this experiment lung ET-1 mRNA levels and lung mRNA expression for the ET(A) receptors were determined in lung tissue weekly (term = 42 days, intervals = 7 days). Serum endothelin concentration was also measured at these ages. Results: The study showed that e...
متن کاملImmunohistochemical Eexpression of Endothelin A Receptor in Dysplastic Oral Mucosa
Background: Recent researches have provided evidences of the importance of endothelin axis in carcinogenesis. According to our knowledge, no data exists about endothelin A receptor (ETA) expression in dysplastic oral mucosa (DOM). Therefore, the aim of the present study was to evaluate immunohistochemical expression of ETA in DOM. Methods:</strong...
متن کاملdevelopmental changes in endothelin-1 and endothelin type a receptor expression in the lungs of chickens (broiler versus layer)
background: broilers lung mechanisms that regulate endothelin (et) in the lung are complex and poorly understood. objectives: methods: in this experiment lung et-1 mrna levels and lung mrna expression for the et(a) receptors were determined in lung tissue weekly (term = 42 days, intervals = 7 days). serum endothelin concentration was also measured at these ages. results: the study showed that e...
متن کاملEndothelin receptor antagonists inhibit endothelin in human skin microcirculation.
Endothelin is a potent vasoconstrictor peptide produced by endothelial cells, but its role in physiology and disease is uncertain. We investigated the influence of the endothelin-A-selective receptor antagonist PD 147953 and the nonselective endothelin receptor antagonist PD 145065 on the effects of endothelin-1 and endothelin-3 in the skin microcirculation of healthy volunteers, using laser Do...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1990
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1990.tb15285.x